1. We see here Gonterman's habit of assigning his own emotions to other people's characters. If only his scope were slightly broader, we might one day see the FoxFire rendition of Lady Macbeth cussing out Shakespeare. One can only hope.
2. It's probably somewhat juvenile to point out, but the poor layout of the page, and the voice balloon specifically, makes it appear that a litany of suffering and mistreatment is being screamed to the heavens by Sally's vagina.